Ex vivo permeation parameters and skin deposition of melatonin-loaded microemulsion for treatment of alopecia
Abstract Background Melatonin (MEL) is a powerful antioxidant molecule with anti-androgenic property.A microemulsion (ME) system loaded with MEL was designed for treatment of androgenic alopecia.Pseudo-ternary phase Jewelry diagram was constructed, and ME formulae were developed using coconut oil, Tween 80 and PEG 400.In the present study, MEL ME w